Dsg2^m3Btlr

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Species

Mus musculus

Symbol

Dsg2^m3Btlr

Category

allele

Allele of gene

Dsg2

Transgenic Constructs

None

Synonyms

• dissolute

Description

ENU-induced T to A transversion at base pair 20,595,951 (v38) on chromosome 18, or base pair 37,878 in the GenBank genomic region NC_000084 within intron 12 (9-base pairs upstream of exon 13 [out of 15 total exons]). The effect of the mutation at the cDNA and protein levels has not been examined, but the mutation is predicted to result in the use of a cryptic site in exon 13. The mutation would cause a 2-base pair deletion of exon 13, causing a frame-shifted protein product beginning after amino acid 632 of the protein, which is normally 1,122 amino acids in length, and termination after the inclusion of 33 aberrant amino acids.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations