Allele/Variant

Arid1bem1Iha

Species
Mus musculus
Symbol
Arid1bem1Iha
Category
allele
Allele of gene
Arid1b
Transgenic Constructs
None
Synonyms
None
Description
CRISPR/Cas9 technology using the Cas9D10A and gRNAs 5'-CCAGGCACAGTACCTGCAGC-3' and 5'-GGCGGGAGGTGCGAGGGCTG-3', generated a deletion in exon 3 that causes a frameshift in translation and premature termination. RNA expression in whole brain of heterozygotes is reduced to about 70% of the level in wild-type while protein is reduced to about 50% of that in wild-type mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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