Allele/Variant

Trim68em1(IMPC)J

Species
Mus musculus
Symbol
Trim68em1(IMPC)J
Category
allele
Allele of gene
Trim68
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTTCTTTCACTAATGTAAGA and TTTTAGGGTAAGGGTCACGT, which resulted in a 2368 bp deletion beginning at Chromosome 7 position 102,679,556 bp and ending after 102,681,923 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000366315 and ENSMUSE00000401581 (exons 4 and 5) and 2084 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 174 and early truncation 66 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations