Version: 8.0.0
Date: Tue Jan 28 2025
Col1a1tm1(tetO-ACMSD)Mmf
MGI:6294155
Allele of Col1a1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Col1a1tm1(tetO-ACMSD)Mmf

Species
Mus musculus
Symbol
Col1a1tm1(tetO-ACMSD)Mmf
Category
allele
Allele of gene
Col1a1
Transgenic Constructs
Synonyms
  • Col1A1tm6(tetO-hACMSD)MMF
Description
RMCE on KH2 ES cells introduced into the 3' UTR a tetracycline-inducible CMV minimal promoter driving inducible expression of the human aminocarboxymuconate semialdehyde decarboxylase cDNA. The ES cells also contain the Gt(ROSA)26Sortm1(rtTA*M2)Jae allele. By treating this mouse line with doxycycline, rtTA*M2 binds the tetO promoter and human aminocarboxymuconate semialdehyde decarboxylase is expressed.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
  • tetO
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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