Allele/Variant

Tg(Myh6*/tetO-Hspb8*K141N)#Atsa

Species
Mus musculus
Symbol
Tg(Myh6*/tetO-Hspb8*K141N)#Atsa
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
The coding region of mouse heat shock protein 8 with the lysine to asparagine missense mutation at amino acid 141 (K141N) with an N-terminal HA tag was inserted into an MHCminTetO-promotor construct. The expression of the construct was driven by a mouse alpha-myosin heavy chain promoter with 3 altered GATA sites and 2 altered thyroid-like response elements for maintaining low levels of cardiac-specific expression, under the control of a tetracycline operator.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations