Allele/Variant

Ltv1em1(IMPC)J

Species
Mus musculus
Symbol
Ltv1em1(IMPC)J
Category
allele
Allele of gene
Ltv1
Transgenic Constructs
None
Synonyms
  • Ltv1-
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGGGGTAACCATGTTCTAGT and TATAGCAGTGGAGCCCAGGC, which resulted in a 314 bp deletion beginning at Chromosome 10 position 13,182,791 bp and ending after 13,183,104 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000098234 (exon 5) and 178 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 132 and early truncation 43 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations