Cep78^em1(IMPC)J

---

Species

Mus musculus

Symbol

Cep78^em1(IMPC)J

Category

allele

Allele of gene

Cep78

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTATAACCATTGTCTAGCTT and GGCATAGCTTGAAGACTGCG, which resulted in a 297 bp deletion beginning at Chromosome 19 position 15,980,964 bp and ending after 15,981,260 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000418400 (exon 4) and 193 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 172 and early truncation 6 amino acids later. There is a single (A) bp insertion at the deletion site.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations