Allele/Variant

Tg(Adipoq-rtTA)2Zvw

Species
Mus musculus
Symbol
Tg(Adipoq-rtTA)2Zvw
Category
allele
Allele of gene
None
Transgenic Constructs
None
Synonyms
  • Adiponectin-rtTA
  • adnP-rtTA
Description
The transgene was designed with an adiponection (Adipoq) promoter driving expression of the reverse tetracycline transactivator gene (rtTA). The 5.4 kb adiponectin promoter is comprised of 200 bp from the 5' end of the first intron linked to 200 bp from the 3' end of the first intron. The 3' end of the promoter is extended beyond the endogenous start codon ATG, which is mutated to ATA to facilitate correct translation initiation.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations