Allele/Variant

Pus7em1(IMPC)J

Species
Mus musculus
Symbol
Pus7em1(IMPC)J
Category
allele
Allele of gene
Pus7
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ACGTCCTGTCCAGGATCATT and GCGTTGGTTGATATGCGCTA, which resulted in a 364 bp deletion beginning at Chromosome 5 position 23,775,824 bp and ending after 23,776,187 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000487336 (exon 3) and 279 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 132 and early truncation 9 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations