Allele/Variant

Bcas1tm1Himo

Species
Mus musculus
Symbol
Bcas1tm1Himo
Category
allele
Allele of gene
Bcas1
Transgenic Constructs
None
Synonyms
  • BCAS1-
Description
A point mutation 12 bases downstream of adenine of the start codon was introduced to generate an in-frame stop codon. A mouse phosphoglycerate kinase promoter-driven neomycin resistantance gene (pgkneo) and a prokaryotic em7 promoter-driven zeocin-resistant gene (em7zeo) was inserted downstream of the engineered point mutation. Western blot analysis confirmed the absence of protein expression in the cerebral cortex and sciatic nerve of homozygote mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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