Mta3^{tm3d(KOMP)Wtsi}

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Species

Mus musculus

Symbol

Mta3^{tm3d(KOMP)Wtsi}

Category

allele

Allele of gene

Mta3

Transgenic Constructs

None

Synonyms

None

Description

The L1L2_gt1 cassette was inserted at position 84045266 of Chromosome 17 upstream of the critical exon 4 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon 4 at position 84046183. The critical exon 4 is thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele. Subsequent cre expression resulted in a knockout mouse. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations