Allele/Variant

Tg(Amelx-icre)876Ppap

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

Amelx-iCre(876)

Description

The transgene was created by modifying BAC by replacing exon 2 of mouse Amelx gene with an improved cre recombinase gene (icre). An FRT-flanked kanomycin resistance cassette was removed prior to injection. 4 independent BAC founder lines (854, 863, 872, and 876) were collected. Line 876 showed the strongest X-gal staining in ameloblasts. However, non-specific staining in the osteoclasts and osteoblasts are noted.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

None

Knock-down Targets

None

Regulatory Regions

Amelx (Mmu)

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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