Allele/Variant

Elp6em1(IMPC)J

Species
Mus musculus
Symbol
Elp6em1(IMPC)J
Category
allele
Allele of gene
Elp6
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTATGAGGAAGGCCTAGCCG and GCCATCCTCCCAGCAAATGA, which resulted in a 1813 bp deletion beginning at Chromosome 9 position 110,312,464 bp and ending after 110,314,276 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000220060 and ENSMUSE00000220064 (exons 3 and 4) and 1623 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 44 and early truncation 18 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations