Allele/Variant

Lyarem1(IMPC)J

Species
Mus musculus
Symbol
Lyarem1(IMPC)J
Category
allele
Allele of gene
Lyar
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTAGGCTGACAGCATGCTAG and GGATCAAGATGGCATTTCCA, which resulted in a 2382 bp deletion beginning at Chromosome 5 position 38,225,848 bp and ending after 38,228,229 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000546144 through ENSMUSE00001264135 (exons 3-5) and 2075 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 41 and early truncation 59 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations