Allele/Variant

Smarcc2em1(IMPC)J

Species
Mus musculus
Symbol
Smarcc2em1(IMPC)J
Category
allele
Allele of gene
Smarcc2
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTATTCTTTTGGACTAAGCG and AAATGTAATTCCTTAAAAGG, which resulted in a 435 bp deletion beginning at Chromosome 10 position 128,462,848 bp and ending after 128,463,282 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000150241 (exon 3) and 349 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 77 and early truncation 21 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations