Allele/Variant

Serpina3iem1(IMPC)J

Species
Mus musculus
Symbol
Serpina3iem1(IMPC)J
Category
allele
Allele of gene
Serpina3i
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AAGGTATATTGACAGCTGTC and TTTACAGGCTATTAGAGAGG, which resulted in a 604 bp deletion beginning at Chromosome 12 position 104,266,357 bp and ending after 104,266,960 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001020941 (exon 4) and 330 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 202 and early truncation 2 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations