Version: 8.0.0
Date: Tue Jan 28 2025
Col1a1tm1(tetO-GFP/RNAi:rluc)Begg
MGI:6368177
Allele of Col1a1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Col1a1tm1(tetO-GFP/RNAi:rluc)Begg

Species
Mus musculus
Symbol
Col1a1tm1(tetO-GFP/RNAi:rluc)Begg
Category
allele
Allele of gene
Col1a1
Transgenic Constructs
None
Synonyms
  • shRNA Ren
Description
RMCE (recombinase-mediated cassette exchange) was utilized to insert tetO-GFP/RNAi:Renilla luciferase (rluc) into the Col1a1 locus. The vector contains a tetracycline responsive promoter (TRE;tetO) controlling expression of a GFP reporter and short-hairpin RNA sequence targeting luciferase embedded in the MIR30 structure. The vector was then co-electroporated with a FLPe recombinase-expressing vector into the RMCE-ready KH2 ES cells.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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