Allele/Variant

Rrhtm1Ght

Species
Mus musculus
Symbol
Rrhtm1Ght
Category
allele
Allele of gene
Rrh
Transgenic Constructs
None
Synonyms
  • Rrh-
Description
Using homologous recombination in ES cells, a targeting vectir replaced a 4.3-kb fragment starting at the initiator methionine in exon 1 and a part of intron 1 of a mouse Rrh genomic fragment with a LacZ-coding region followed by a neomycin resistance cassette (PGK-Neo). Immunoblot analysis on retinal pigment epithelium (RPE) homogenates and immunohistochemistry of eyecup sections confirmed absence of protein in homozygous mice. It is a null allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations