Rrh^tm1Ght

---

Species

Mus musculus

Symbol

Rrh^tm1Ght

Category

allele

Allele of gene

Rrh

Transgenic Constructs

None

Synonyms

• Rrh^-

Description

Using homologous recombination in ES cells, a targeting vectir replaced a 4.3-kb fragment starting at the initiator methionine in exon 1 and a part of intron 1 of a mouse Rrh genomic fragment with a LacZ-coding region followed by a neomycin resistance cassette (PGK-Neo). Immunoblot analysis on retinal pigment epithelium (RPE) homogenates and immunohistochemistry of eyecup sections confirmed absence of protein in homozygous mice. It is a null allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations