Version: 8.0.0
Date: Tue Jan 28 2025
Phf8tm1.1Cdcn
MGI:6370001
Allele of Phf8
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Phf8tm1.1Cdcn

Species
Mus musculus
Symbol
Phf8tm1.1Cdcn
Category
allele
Allele of gene
Phf8
Transgenic Constructs
None
Synonyms
None
Description
Exons 7 and 8, encoding the code region of the JmjC demethylase domain, were flanked by loxP sites. A FRT-flanked neomycin resistance gene was inserted downstream of exon 8 before the second loxP site. Cre-mediated recombination deleted exons 7 and 8 and the selection cassette in the germline. Western blot and immunostaining on brains confirmed absence of protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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