Tdrd3^em1(IMPC)J

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Species

Mus musculus

Symbol

Tdrd3^em1(IMPC)J

Category

allele

Allele of gene

Tdrd3

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCATTGATACACATATAGAT and TCCACCCAACCCTTAACACA, which resulted in a 2230 bp deletion beginning at Chromosome 14 position 87,485,304 bp and ending after 87,487,533 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000122962-ENSMUSE00000122958 (exons 8-10) and 1806 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 239 and early truncation 23 amino acids later.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations