Allele/Variant

Wdr25em1(IMPC)J

Species
Mus musculus
Symbol
Wdr25em1(IMPC)J
Category
allele
Allele of gene
Wdr25
Transgenic Constructs
None
Synonyms
  • Wdr25-
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TAGCAGACTGTCGAAGGCAG and CAAATGATCTGCATGCCCGT, which resulted in a 672 bp deletion beginning at Chromosome 12 position 108,980,296 bp and ending after 108,980,967 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000879483 (exon 4) and 524 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 265 and early truncation 15 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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