Allele/Variant

Ppa2em1(IMPC)J

Species
Mus musculus
Symbol
Ppa2em1(IMPC)J
Category
allele
Allele of gene
Ppa2
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ATAAAGAGCAGCGCGCGCGG and ACTGCCCCATTCTAGCTCCT, which resulted in a 223 bp deletion beginning at Chromosome 3 position 133,320,903 bp and ending after 133,321,125 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001248779 (exon 2) and 158 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 47 and early truncation 2 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations