Allele/Variant

Brd3em1(IMPC)J

Species
Mus musculus
Symbol
Brd3em1(IMPC)J
Category
allele
Allele of gene
Brd3
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGCAACAGTAAAAACTTAGA and TGTTAAGAGATTTGTCATGG, which resulted in a 352 bp deletion beginning at Chromosome 2 position 27,462,338 bp and ending after 27,462,689 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001283892 (exon 4) and 204 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 116 and early truncation 69 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations