Allele/Variant

Tg(Camk2a-MAPT*P301L)#Atak

Species
Mus musculus
Symbol
Tg(Camk2a-MAPT*P301L)#Atak
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • P301L-Tg
  • P301Ltau-Tg
Description
The human 4 repeat tau containing the P301L mutation and myc and FLAG tags at the N- and C-terminals, respectively, is under the control of the Camk2 promoter. The pound symbol (#) is used when line is not specified and/or lines are pooled. Mice show a 3-5-fold overexpression of the mutant tau relative to endogenous mouse tau.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations