Slc22a15^em1(IMPC)J

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Species

Mus musculus

Symbol

Slc22a15^em1(IMPC)J

Category

allele

Allele of gene

Slc22a15

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GTTATGGAAATACTAAGGGG and GCATTTCTGAAGCTTGGATA, which resulted in a 371 bp deletion beginning at Chromosome 3 position 101,897,863 bp and ending after 101,898,233 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000519337 (exon 3) and 184 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 100 and early truncation 22 amino acids later.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations