Hspb8^tm1.1Vti

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Species

Mus musculus

Symbol

Hspb8^tm1.1Vti

Category

allele

Allele of gene

Hspb8

Transgenic Constructs

None

Synonyms

• Hspb8^-

Description

A loxP site, a mutated exon 2 containing a G to C change at position 423 resulting in a lysine to asparagine mutation at amino acid 141 (K141N), an FRT-flanked neomycin selection cassette, and a loxP site replaced exon 2. Cre-mediated recombination removed the mutated exon 2 and the neomycin gene resulting in a null allele. Western blot analysis confirmed absence of protein.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations