Allele/Variant

Hspb8tm1.1Vti

Species
Mus musculus
Symbol
Hspb8tm1.1Vti
Category
allele
Allele of gene
Hspb8
Transgenic Constructs
None
Synonyms
  • Hspb8-
Description
A loxP site, a mutated exon 2 containing a G to C change at position 423 resulting in a lysine to asparagine mutation at amino acid 141 (K141N), an FRT-flanked neomycin selection cassette, and a loxP site replaced exon 2. Cre-mediated recombination removed the mutated exon 2 and the neomycin gene resulting in a null allele. Western blot analysis confirmed absence of protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations