Allele/Variant

Dnaaf3em1(IMPC)J

Species
Mus musculus
Symbol
Dnaaf3em1(IMPC)J
Category
allele
Allele of gene
Dnaaf3
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTAACCCTAGGCCACAGTAG and TCTCTGAAAAATCTTGCCCA, which resulted in a 617 bp deletion beginning at Chromosome 7 position 4,527,750 bp and ending after 4,528,366 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000419696 (exon 5) and 459 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 107 and early truncation 21 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations