Version: 8.0.0
Date: Tue Jan 28 2025
Dpp4em1Rba
MGI:6400423
Allele of Dpp4
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Dpp4em1Rba

Species
Mus musculus
Symbol
Dpp4em1Rba
Category
allele
Allele of gene
Dpp4
Transgenic Constructs
None
Synonyms
  • 288/330+
Description
CRISPR/Cas9 technology introduced two amino acid changes, an alanine to leucine substitution at amino acid 288 (A288L) in exon 10 and a threonine to arginine substitution at amino acid 330 (T330R) in exon 11. These two changes match the human sequence, making mice susceptible to Middle East respiratory syndrome coronavirus infection and replication.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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