Allele/Variant

Gid8em1(IMPC)J

Species
Mus musculus
Symbol
Gid8em1(IMPC)J
Category
allele
Allele of gene
Gid8
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TCAGGATGCCAGAGCAACAG and GCGCTGCTCTTCCTCTCACA, which resulted in a 2882 bp deletion beginning at Chromosome 2 position 180,714,342 bp and ending after 180,717,223 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000170682 and ENSMUSE00000170684 (exons 2 and 3) and 2487 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 39 and early truncation 3 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations