Eif2b5^tm2.1Sidr

---

Species

Mus musculus

Symbol

Eif2b5^tm2.1Sidr

Category

allele

Allele of gene

Eif2b5

Transgenic Constructs

None

Synonyms

• Eif2b5^R132H

Description

Residue arginine 132 was changed to histamine, loxP sites were inserted flanking some of the exons including the mutation, and a FRT-flanked neomycin resistance cassette was inserted upstream of the mutation. The neomycin resistance cassette was removed via flp-mediated recombination. The R132H mutation corresponds to the vanishing white matter causing human R136H allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations