Version: 8.0.0
Date: Tue Jan 28 2025
Tg(S1pr2-cre/ERT2)#Kuro
MGI:6435090Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(S1pr2-cre/ERT2)#Kuro

Species
Mus musculus
Symbol
Tg(S1pr2-cre/ERT2)#Kuro
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • S1pr2-ERT2cre
Description
An ERT2cre-encoding gene fused with a poly(A) signal and a neomycin-kanamycin resistance gene flanked with two FRT sites were inserted into the exon 2 of the S1pr2 gene, which encodes S1P2, on a BAC clone (RPCI23.C-168D6). Correctly targeted clones were injected into pronuclei of C57BL/6 zygotes to generate transgenic funder lines. The founder mice were identified by PCR and were further crossed with CAG-Flp transgenic mice to remove the neomycin-kanamycin resistance gene cassette. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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