Allele/Variant

Tg(Thy1/THY1)mhT4Gsv

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

mhT4

Description

This transgene consists of a hybrid Thy1 gene which contains 1.5 kb 5' flanking sequences of the murine Thy1 gene, a 5.7 kb EcoRI-ApaI mouse Thy1^a (Thy1.1) gene fragment containing the first 4 exons (including exons 1a and 1b) and part of exon 4 that is fused to a 3.4 kb ApaI-EcoRI human THY1 DNA sequence containing the remaining noncoding part of exon IV plus 3' human flanking sequence. High levels of hybrid transgene expression is seen in glomerular podocytes.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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