Allele/Variant

Tg(Thy1/THY1)hT10Gsv

Species
Mus musculus
Symbol
Tg(Thy1/THY1)hT10Gsv
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • hT10
Description
This transgene is a hybrid Thy1 gene in which a 0.8 kb BstEII-ApaI fragment containing part of exons 3 and 4 of the mouse gene was replaced with the homologous 0.96 kb BstEII-ApaI human THY1 gene fragment (containing the mature protein and transmembrane sequences) while the 5' and 3' flanking regions are mouse sequences. High expression of the hybrid transgene is seen in the kidney proximal tubular epithelium and in the brain.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations