Ikzf4^tm1.1Etms

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Species

Mus musculus

Symbol

Ikzf4^tm1.1Etms

Category

allele

Allele of gene

Ikzf4

Transgenic Constructs

None

Synonyms

• Eos^-

Description

The last three exons, 6-8, were replaced with the following: a loxP site flanked neomycin resistance gene cassette, exon 8 splice acceptor sequence, IRES sequence, and the lacZ reporter gene. This creates a reporter-knockout allele. The neo cassette was removed through cre-mediated recombination. Lack of mRNA and protein expression from this allele was confirmed.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations