Version: 8.0.0
Date: Tue Jan 28 2025
Adamts17tm1.2Taks
MGI:6466717
Allele of Adamts17
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Adamts17tm1.2Taks

Species
Mus musculus
Symbol
Adamts17tm1.2Taks
Category
allele
Allele of gene
Adamts17
Transgenic Constructs
None
Synonyms
None
Description
A loxP site was inserted upstream of exon 4, and an FRT-flanked neomycin selection cassette and a second loxP site were inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette and cre-mediated recombination in the germline deleted exon 4. Deletion of exon 4 generates a frame-shift leading to disruption of the zinc-dependent metalloprotease domain and its downstream sequences.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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