Bicral^em1(IMPC)J

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Species

Mus musculus

Symbol

Bicral^em1(IMPC)J

Category

allele

Allele of gene

Bicral

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ACCTTGTGACTGACAGGAGA and ATTTTTAGCTCACCAAGCAA, which resulted in a 532 bp deletion beginning at Chromosome 17 position 46,829,784 bp and ending after 46,830,315 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000424961, ENSMUSE00000424956 (exons 2,3) and 414 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 14 and early truncation 10 amino acids later.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations