Rtp4^em#Xzs

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Species

Mus musculus

Symbol

Rtp4^em#Xzs

Category

allele

Allele of gene

Rtp4

Transgenic Constructs

None

Synonyms

• Rtp4^-

Description

The first and second coding exons (1 and 2) were targeted with two sgRNAs (5′-ccccgatgacttcagtacttggg-3′ and 5′- cctcagacccggaatacggatttt-3′) using CRISPR/Cas9 technology. Five founder mice were created with at least two different size deletions, both including the end of exon 1, intron 1 and the start of exon 2. The pound # sign is used in the allele symbol because which mouse line was used, or if a mixture was used, is not specified.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations