Version: 8.0.0
Date: Tue Jan 28 2025
Trp53tm2Thst
MGI:6479073
Allele of Trp53
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Trp53tm2Thst

Species
Mus musculus
Symbol
Trp53tm2Thst
Category
allele
Allele of gene
Trp53
Transgenic Constructs
None
Synonyms
  • p53LSL-EE
  • p53LSL-R178E
Description
Exon 5 was replaced with a modified one in which nucleotide substitutions CGC-to-GAG result in the amino acid substitution of arginine with glutamic acid at position 178 (p.R178E). A loxP site flanked STOP cassette was inserted into intron 1.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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