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Date: Tue Jan 28 2025
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Trp53
tm2Thst
MGI:6479073
Allele of
Trp53
Mus musculus
Summary
Transgenic Constructs
Genomic Variant Information
Variant Molecular Consequences
Phenotypes
Disease Associations
Allele/Variant
Trp53
tm2Thst
Species
Mus musculus
Symbol
Trp53
tm2Thst
Category
allele
Allele of gene
Trp53
Transgenic Constructs
None
Synonyms
p53LSL-EE
p53LSL-R178E
Show All 3
Description
Exon 5 was replaced with a modified one in which nucleotide substitutions CGC-to-GAG result in the amino acid substitution of arginine with glutamic acid at position 178 (p.R178E). A loxP site flanked STOP cassette was inserted into intron 1.
Additional Information
Literature
Transgenic Constructs
No data available
Genomic Variant Information
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Variant Molecular Consequences
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