Allele/Variant

Map9tm1.2Bcgen

Species
Mus musculus
Symbol
Map9tm1.2Bcgen
Category
allele
Allele of gene
Map9
Transgenic Constructs
None
Synonyms
  • Map9delta
Description
A gene trap cassette, consisting of an FRT site, an engrailed 2 splice acceptor site, IRES, EGFP, a loxP site, a neomycin selection gene, another FRT site and a loxP flanked exon 5, was inserted into intron 4. Flp-mediated recombination removed the EGFP and neomycin gene, leaving exon 5 floxed. Exon 5 was removed via cre-mediated recombination in the germline resulting in a frameshift and premature stop codon in exon 6. qPCR confirmed the absence of mRNA in homozygotes.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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