Allele/Variant

Nlrc4em2Vnce

Species
Mus musculus
Symbol
Nlrc4em2Vnce
Category
allele
Allele of gene
Nlrc4
Transgenic Constructs
None
Synonyms
  • Nlrc4em2(S533A)Vnce
  • Nlrc4S533A
Description
Serine codon 533 (TCA) was targeted with an sgRNA (targeting CTCTGGAGGCAGGAATCAAT) and ssODN templates using CRISPR/Cas9 technology, changing it to alanine codon GCA (p.S533A). This mutation renders the encoded peptide nonphosphorylatable at this residue. Western blot experiments confirmed the expression of peptides from this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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