Allele/Variant

Dsc2tm1.2Leu

Species
Mus musculus
Symbol
Dsc2tm1.2Leu
Category
allele
Allele of gene
Dsc2
Transgenic Constructs
None
Synonyms
  • Dsc2-
Description
A loxP site was inserted into intron 1 and an FRT site flanked neomycin selection cassette and a second loxP site into intron 2. The neo cassette was removed via flp-mediated recombination and exon 2 was deleted via cre-mediated recombination in the germline. Western blot and qRT-PCR experiments confirmed the lack of peptide and transcript expression from this allele in liver and heart.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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