Version: 8.0.0Date: Tue Jan 28 2025
Allele/Variant
Tg(Hspa1b-flpo)A4Kht
- Species
- Mus musculus
- Symbol
- Tg(Hspa1b-flpo)A4Kht
- Category
- allele
- Allele of gene
- None
- Transgenic Constructs
- Synonyms
- HSE-FLPo
- Description
- The transgenic construct contains a codon-optimized flp recombinase followed by a bGH polyadenylation (polyA) sequence under the direction of the murine heat shock response element (Hspa1b, formerly Hsp70-1) promoter/enhancer sequences .Founder line A4 was then selected for consistent expression. Analysis using shallow whole-genome sequencing suggests that the transgene integrated into an intronic region of the Tcerg locus on chromosome 18, and in the opposite orientation to the surrounding region.
- Additional Information
- Literature
Transgenic Constructs
This allele contains 1 transgenic construct- Symbol
- Expressed Components
- None
- Knock-down Targets
- None
- Regulatory Regions