Allele/Variant

Tg(CAG-cat,-Trim8)4Holi

Species
Mus musculus
Symbol
Tg(CAG-cat,-Trim8)4Holi
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • CAG-CAT-TRIM8
Description
The transgene contains the following elements: the CAG promoter, a loxP site, a cat (chloramphenicol acetyltransferase) gene and polyA signal sequences, a second loxP site, and a mouse Trim8 cDNA and polyA signal sequences. This transgene allele normally expresses the cat gene: only after cre-mediated removal of the cat gene will it express the Trim8 gene. Four mouse lines (1-4) were established and line 4, which has the highest increase in Trim8 peptide expression after induction, was selected for further study.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations