Vps13b^em1Yosl

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Species

Mus musculus

Symbol

Vps13b^em1Yosl

Category

allele

Allele of gene

Vps13b

Transgenic Constructs

None

Synonyms

• Vps13b^2-

Description

Exon 2 was targeted with two sgRNAs (targeting ACGCTTAAATTTGAAGATGCTGG and CGAGTTAAAGTTGGACGTTCTGG) using CRISPR/Cas9 technology, resulting in a 156 bp deletion that includes the start codon. Absence of exon 2 expression in the hippocampus was confirmed by RT-PCR.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations