Allele/Variant

Impacttm1.1Casb

Species
Mus musculus
Symbol
Impacttm1.1Casb
Category
allele
Allele of gene
Impact
Transgenic Constructs
None
Synonyms
None
Description
A loxP site was inserted upstream of exon 3 and a loxP site and pgk-neo cassette were inserted downstream of exon 4 via homologous recombination. Recombinase mediated recombination removed exons 3 and 4. Western blot analysis confirmed the absence of protein expression in the heart, liver, and brain of homozygous mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations