Slc48a1^em1Ih

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Species

Mus musculus

Symbol

Slc48a1^em1Ih

Category

allele

Allele of gene

Slc48a1

Transgenic Constructs

None

Synonyms

• M6

Description

CRISPR/cas9 mediated recombination created a 2 bp deletion in exon 1 resulting in a frameshift mutation in the region after the first transmembrane domain. While mRNA was detected immunoblot and immunohistochemical analysis confirmed the absence of protein in reticuloendothelial tissues from homozygous mice.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations