St8sia3^em1Yich

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Species

Mus musculus

Symbol

St8sia3^em1Yich

Category

allele

Allele of gene

St8sia3

Transgenic Constructs

None

Synonyms

• St8sia3-KO
• St8sia3^-

Show All 3

Description

Exon 3 and exon/intron 4 were targeted with two sgRNAs using CRISPR/Cas9 technology, resulting in a 1966 bp deletion, encompassing most of exon 3 (which contains the ATG start site) and the entirety of intron 3 and exon 4, and 18 bp insertion. Immunoblots confirmed the absence of peptide expression from this allele in the brain.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations