Allele/Variant

Gpr182tm2c(KOMP)Wtsi

Species
Mus musculus
Symbol
Gpr182tm2c(KOMP)Wtsi
Category
allele
Allele of gene
Gpr182
Transgenic Constructs
None
Synonyms
  • Gpr182flox
Description
The L1L2_Bact_P cassette was inserted at position 127585300 of Chromosome 10 upstream of the critical exon 2 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon 2 at position 127587278. The critical exon 2 is thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml .
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations