Allele/Variant

Ccdc6tm1Afus

Species
Mus musculus
Symbol
Ccdc6tm1Afus
Category
allele
Allele of gene
Ccdc6
Transgenic Constructs
None
Synonyms
  • Ccdc6-ex2
Description
An approximate 12 kb genomic region containing exon 2 was replaced with a neomycin-resistance cassette in the opposite transcriptional orientation of the endogenous gene. RT-PCR analysis confirmed the presence of an exon 2 deleted transcript and Western blot shows the expression of a truncated protein. The deletion of exon 2 which contains the coiled-coil domain results in increased CREB1 transcriptional activity.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page