Allele/Variant

Pfn4em2Hsc

Species
Mus musculus
Symbol
Pfn4em2Hsc
Category
allele
Allele of gene
Pfn4
Transgenic Constructs
None
Synonyms
  • Pfn4deltab
Description
CRISPR-targeting of exons 2 through 4 deleted 5417 bp leading to generation of a 5' truncated nonsense protein. qRT-PCR analysis confirmed the absence of mRNA expression in the testes of homozygous mutant males.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal acrosome assembly
MGI
abnormal acrosome morphology
MGI
abnormal Golgi apparatus morphology
MGI
abnormal Golgi vesicle transport
MGI
abnormal manchette assembly
MGI
abnormal manchette morphology
MGI
abnormal proacrosomal vesicle fusion
MGI
abnormal sperm connecting piece morphology
MGI
abnormal sperm flagellum morphology
MGI
abnormal sperm head morphology
MGI
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Disease Associations

No data available